Is it safe to take injectable ivermectin by mouth instead of as an injection?

Can I Take Injectable Ivermectin Orally?

Ivermectin is an antiparasitic medication that has been widely used to treat various infectious diseases, particularly those caused by parasitic worms and certain external parasites like lice and scabies. Recently, it has gained attention for its potential role in combating viral infections, most notably during the COVID-19 pandemic. This interest has led to questions about the different formulations of ivermectin, and whether it can be taken orally when it is available in injectable form.

Understanding Ivermectin Formulations

Ivermectin is available in several forms, including oral tablets, topical creams, and injectable solutions. The oral form is typically used in humans for the treatment of conditions like river blindness and lymphatic filariasis, while the injectable form is primarily administered to livestock and other animals to control parasitic infections. The key difference between these formulations lies in their concentration, purity, and intended use.

Injectable ivermectin is designed for specific dosing requirements in animals, which may differ significantly from human dosing needs. The compositions and excipients in veterinary formulations may not be safe or effective for human consumption. Thus, it's crucial to understand the implications of using injectable ivermectin orally.

Risks of Taking Injectable Ivermectin Orally

1. Safety Concerns Injectable ivermectin may contain ingredients that are not safe for human consumption. Unlike pharmaceutical preparations approved for human use, animal medications are not subject to the same stringent regulations, which increases the risk of contamination or harmful additives.

2. Dosing Issues The appropriate dosage for animals differs from that for humans. Taking injectable ivermectin at an animal dosage can lead to underdosing, which may result in treatment failure, or overdosing, which can cause serious side effects. Overdosing can lead to neurological issues, seizures, or even death.

3. Absorption and Efficacy The pharmacokinetics of injectable ivermectin differ from that of oral formulations. Injectable ivermectin is designed for rapid absorption directly into the bloodstream, whereas oral forms are formulated for gradual release and absorption through the digestive system. Taking the injectable form orally may lead to altered drug levels, reduced efficacy, and increased toxicity.

4. Lack of Clinical Evidence There is a lack of scientific research supporting the safety or efficacy of taking injectable ivermectin orally in humans. Most studies that evaluate ivermectin's use focus on the approved oral formulations.

Regulatory Perspective

Health authorities and regulatory bodies, such as the Food and Drug Administration (FDA) and the World Health Organization (WHO), caution against using injectable ivermectin intended for animals as a treatment for humans. Misuse of veterinary medications has been linked to various health complications and underscores the importance of using approved pharmaceuticals specifically designed for human use.

The Bottom Line

Taking injectable ivermectin orally is not recommended due to safety concerns, dosing discrepancies, absorption issues, and the lack of supporting evidence for its efficacy in humans. Individuals considering ivermectin for any purpose should consult with a healthcare professional who can provide guidance on the appropriate formulation and dosage based on individual health needs.

In conclusion, while ivermectin is a valuable medication in the treatment of certain parasitic infections, it must be used appropriately and safely. Always rely on medically approved formulations specifically designed for human use and seek professional medical advice before self-medicating.