Colistin Sulfate ufa wosungunuka

Mucin

Mankhwalawa ndi oyera kapena pafupifupi ufa woyera.

Pharmacodynamics Myxin ndi mtundu wa polypeptide antibacterial wothandizira, womwe ndi mtundu wa zamchere cationic surfactant. Kudzera mogwirizana ndi phospholipids mu bakiteriya cell nembanemba, izo likulowerera mu bakiteriya selo nembanemba, kuwononga dongosolo lake, ndiyeno kumayambitsa kusintha kwa nembanemba permeability, kumabweretsa imfa bakiteriya ndi bactericidal kwenikweni.

Mankhwalawa amagwira ntchito motsutsana ndi mabakiteriya a aerobic, Escherichia coli, haemophilus, Klebsiella, Pasteurella, Pseudomonas aeruginosa.

Mabakiteriya a gram-negative monga mabakiteriya, salmonella ndi shigella ali ndi antibacterial effect. Gram positive bacilli.Nthawi zambiri samamva. Panali kukana kwathunthu kwa mtanda ndi polymyxin B, koma panalibe kukana kwa mtanda ndi maantibayotiki ena.

Pharmacokinetics: Kugwiritsa ntchito m'kamwa sikumayamwa mankhwalawo, koma osagwiritsa ntchito m'mimba amamwa mwachangu. Mankhwala omwe amalowa m'thupi akhoza kukhala mofulumira.Ikhoza kulowa mu mtima, m'mapapo, chiwindi, impso ndi chigoba mofulumira, koma sikophweka kulowa mu ubongo, msana, chifuwa, mafupa olumikizana ndi zomverera.

Infected foci. Iwo makamaka excreted kudzera impso.

(1) Kuphatikizidwa ndi zotsitsimutsa minofu ndi neuromuscular blockers monga aminoglycosides zingayambitse kufooka kwa minofu ndi kupuma.
(2) Imakhala ndi synergistic effect ndi chelating agent (EDTA) ndi cationic cleaner pa Pseudomonas aeruginosa, ndipo imagwiritsidwa ntchito nthawi zambiri pochiza matenda a m'deralo.

Peptide antibiotics. Amagwiritsidwa ntchito kwambiri pochiza matenda am'mimba omwe amayamba chifukwa cha mabakiteriya a gram-negative.

Kuwerengeredwa ndi mankhwalawa. Kumwa kosakaniza: 0,4 ~ 2g nkhumba ndi 0,2 ~ 0.6g nkhuku pa 1L madzi; Kudyetsa kosakaniza: 0,4 ~ 0.8g pa 1kg chakudya cha nkhumba.

Palibe zoyipa zomwe zidapezeka zikagwiritsidwa ntchito molingana ndi momwe amagwiritsidwira ntchito komanso mlingo wake.

(1) Nkhuku zoikira mazira kuti anthu adye siziyenera kugwiritsidwa ntchito panthawi yoikira.

(2) Kugwiritsa ntchito mosalekeza sikuyenera kupitirira sabata imodzi.

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