Phofo e qhibilihang ea Amoxicillin
Amoxicillin
Sehlahisoa sena ke phofo e tšoeu kapa e batlang e le tšoeu.
Pharmacodynamics Amoxicillin ke lithibela-mafu tsa B-lactam tse nang le phello e matla ea antibacterial. Sehlahisoa sa antibacterial le ts'ebetso ha e le hantle li tšoana le ampicillin. Ts'ebetso ea antibacteria khahlano le libaktheria tse ngata tsa gram-positive e fokola hanyane ho feta penicillin, 'me e na le kutloelo-bohloko ho penicillinase, kahoo ha e sebetse khahlano le Staphylococcus aureus e hanyetsanang le penicillin. E na le phello e matla ho libaktheria tsa gram-negative tse kang Escherichia coli, Proteus, Salmonella, Haemophilus, Brucella le Pasteurella, empa libaktheria tsena li na le bothata ba ho hanyetsa lithethefatsi. Ha e nahanele Pseudomonas aeruginosa. Hobane ho monya ha eona ho liphoofolo tse monogastric ho molemo ho feta ampicillin, 'me khatello ea mali ea eona e phahame, e na le phello e ntle ho ts'oaetso ea systemic. E sebetsa tsamaisong ea ho hema, tsamaiso ea moroto, mafu a letlalo le lisele tse bonolo tse bakoang ke libaktheria tse hlokolosi.
Pharmacokinetics: amoxicillin e tsitsitse ho acidic gastric, e monngoang ke 74% ~ 92% kamora ho tsamaisoa ka molomo ho liphoofolo tse monogastric. Likahare tsa pampitšana ea mala li ama sekhahla sa ho monya, empa ha li ame tekanyo ea ho monya, ka hona ho ka sebelisoa phepelo e tsoakiloeng. Kamora ho tsamaisoa ka molomo ka tekanyetso e ts'oanang, khatello ea serum ea amoxicillin e ne e phahame makhetlo a 1.5-3 ho feta ea ampicillin.
(1) Motsoako oa sehlahisoa sena le li-aminoglycosides li ka eketsa bongata ba libaktheria, ho bonts'a phello ea synergistic.
(2) Li-bacteriostatic agents tse sebetsang ka potlako tse kang macrolides, tetracyclines le amide alcohols li kena-kenana le phello ea bactericidal ea sehlahisoa sena 'me ha lia lokela ho sebelisoa hammoho.
lithibela-mafu tsa β-Lactam. E sebelisoa ho phekola tšoaetso ea libaktheria tsa gram-positive le libaktheria tsa gram-negative tse amehang ho amoxicillin likhoho.
E baloang ke sehlahisoa sena. Nka ka molomo: 0.2 ~ 0.3g khoho ka 1kg boima ba 'mele. makhetlo a 2 ka letsatsi bakeng sa matsatsi a 5 a latellanang: seno se tsoakiloeng: 0.6g ea khoho ka metsi a 1L bakeng sa matsatsi a 3 ho isa ho a 5 a latellanang.
E na le phello e matla ea ho kena-kenana le limela tse tloaelehileng tsa pampiri ea gastrointestinal.
(1) Likhoho tse behelang mahe ho jeoa ke batho li ke ke tsa sebelisoa nakong ea ho behela.
(2) Libaktheria tsa gram-positive tse hanyetsanang le penicillin ha lia lokela ho sebelisoa.
(3) E loketse ho sebelisoa.
Aterese:No.2 Xingding Road, Dingzhou City, Shijiazhuang, Hebei China
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