I-Amoxicillin Powder Encibilikayo

I-Amoxicillin

Lo mkhiqizo umhlophe noma ucishe ube yimpushana emhlophe.

I-Pharmacodynamics I-Amoxicillin iyi-antibiotic ye-B-lactam enomphumela obanzi we-antibacterial. I-spectrum ye-antibacterial kanye nomsebenzi ngokuyisisekelo kuyafana ne-ampicillin. Umsebenzi we-antibacterial ngokumelene namagciwane amaningi egram-positive ubuthakathaka kancane kune-penicillin, futhi uyazwela ku-penicillinase, ngakho awusebenzi ekumelaneni ne-penicillin i-Staphylococcus aureus. Inomthelela oqinile kumagciwane e-gram-negative afana ne-Escherichia coli, i-Proteus, i-Salmonella, i-Haemophilus, i-Brucella ne-Pasteurella, kodwa la magciwane ajwayele ukumelana nemithi. Ayizweli ku-Pseudomonas aeruginosa. Ngenxa yokuthi ukumuncwa kwayo ezilwaneni ze-monogastric kungcono kune-ampicillin, futhi ukugcwala kwayo egazini kuphezulu, kunomthelela ongcono ekuthelelekeni kwesistimu. Isebenza ohlelweni lokuphefumula, uhlelo lokuchama, izifo zesikhumba kanye nezicubu ezithambile ezibangelwa amagciwane azwelayo.

I-Pharmacokinetics: i-amoxicillin izinzile impela ku-asidi yesisu, emuncwa ngama-74% ~ 92% ngemuva kokuphathwa ngomlomo ezilwaneni ezinegastric. Okuqukethwe kwepheshana lamathumbu kuthinta izinga lokumunca, kodwa akuthinti izinga lokumunca, ngakho-ke ukudla okuxubile kungasetshenziswa. Ngemuva kokuphathwa ngomlomo komthamo ofanayo, ukugcwala kwe-amoxicillin ku-serum kwakuphindwe izikhathi eziyi-1.5-3 kune-ampicillin.

(1) Inhlanganisela yalo mkhiqizo kanye nama-aminoglycosides kungakhuphula ukugcwala kokugcina kubhaktheriya, okubonisa umthelela we-synergistic.

(2) Ama-bacteriostatic asebenza ngokushesha njengama-macrolides, ama-tetracycline nama-amide alcohols aphazamisa umphumela wokubulala amagciwane walo mkhiqizo futhi akufanele asetshenziswe ndawonye.

Ama-antibiotic e-β-Lactam. Isetshenziselwa ukwelapha ukutheleleka kwamagciwane e-gram-positive kanye namagciwane e-gram-negative azwela i-amoxicillin ezinkukhu.

Kubalwe yilo mkhiqizo. Thatha ngomlomo: 0.2 ~ 0.3g yenkukhu nge-1kg yesisindo somzimba. Izikhathi ezi-2 ngosuku izinsuku ezi-5 ezilandelanayo: isiphuzo esixutshwe: 0.6g yenkukhu nge-1L yamanzi izinsuku ezi-3 kuya kwezi-5 ezilandelanayo.

Inomphumela oqinile wokuphazamisa esitshalweni esivamile sepheshana lesisu.

(1) Izinkukhu ezizalela amaqanda ukuze zidliwe abantu akufanele zisetshenziswe ngesikhathi sokuzalela.

(2) Amagciwane e-Gram positive amelana ne-penicillin akufanele asetshenziswe.

(3) Ilungele ukusetshenziswa.

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