Levamisole 1000mg Bolus

I-Levamisole imuncwa emathunjini ngemva kokufakwa ngomlomo nangesikhumba ngemva kokufakwa kwesikhumba, nakuba amandla e-bioavailability ayahlukahluka. Kubikwa ukuthi isatshalaliswa emzimbeni wonke. I-Levamisole igaywe i-metabolism ngokungaphansi kuka-6% ekhishwe engashintshiwe emchameni. Ukuphila kwesigamu sokuqedwa kwe-plasma kunqunywe ngezinhlobo eziningana zezilwane: Izinkomo amahora angu-4-6; Izinja amahora angu-1.8-4; futhi Swine 3.5-6.8 amahora. Ama-metabolites akhishwa kuwo womabili umchamo (ikakhulukazi) nasendle.

I-Levamisole ikhonjiswe ekwelapheni ama-nematode amaningi ezinkomo, izimvu nezimbuzi, izingulube, izinkukhu. Ezimvini nasezinkomeni, i-levamisole inomsebenzi omuhle uma iqhathaniswa ne-abomasal nematodes, i-nematodes yamathumbu amancane (ayilungile kakhulu ngokumelene ne-Strongyloides spp.), i-nematodes yamathumbu amakhulu (hhayi i-Trichuris spp.), kanye nezikelemu zamaphaphu. Izinhlobo zezinhlobo zabantu abadala ezivame ukumbozwa i-levamisole, zifaka: Haemonchus spp., Trichostrongylus spp., Osteragia spp., Cooperia spp., Nematodirus spp., Bunostomum spp., Oesophagostomum spp., Chabertia spp., ne-Dictyopurus. I-Levamisole ayisebenzi kahle ezinhlotsheni ezingavuthiwe zalezi zimuncagazi futhi ngokuvamile ayisebenzi ezinkomeni (kodwa hhayi ezimvini) ngokumelene nezinhlobo zezibungu eziboshiwe.

Ezingulubeni, i-levamisole iboniswa ekwelapheni i-Ascaris suum, i-Oesophagostomum spp., i-Strongyloides, i-Stephanurus, ne-Metastrongylus.

I-Levamisole isetshenziswe ezinjeni njenge-microfilaricide ukwelapha ukutheleleka kwe-Dirofilaria immitis.

I-Levamisole iphikisana nezilwane ezincelisayo. Kufanele isetshenziswe ngokuqapha, uma kunjalo, ezilwaneni eziwohloke kakhulu, noma ezinokukhubazeka okukhulu kwezinso noma kwesibindi. Sebenzisa ngokucophelela noma, okungcono, ukubambezela ukusetshenziswa kwezinkomo ezicindezelekile ngenxa yokugoma, ukukhipha izimpondo noma ukuthenwa.

Alukho ulwazi mayelana nokuphepha kwalesi sidakamizwa ezilwaneni ezikhulelwe. Nakuba i-levamisole ibhekwa njengephephile uma kuqhathaniswa ukuthi isetshenziswe ezilwaneni ezinkulu ezikhulelwe, sebenzisa kuphela uma izinzuzo ezingaba khona zidlula ubungozi.

Imiphumela emibi engase ibonakale ezinkomeni ingase ihlanganise amafinyila-amagwebu noma i-hypersalivation, injabulo noma ukuthuthumela, ukukhotha izindebe kanye nokunikina ikhanda. Le miphumela ivamise ukuqashelwa ngemithamo ephakeme kunaleyo enconyiwe noma uma i-levamisole isetshenziswa kanye ne-organophosphates. Izimpawu ngokuvamile ziyehla phakathi namahora ama-2. Lapho ujova izinkomo, ukuvuvukala kungase kwenzeke endaweni yomjovo. Lokhu ngokuvamile kuzophela ezinsukwini ezingu-7-14, kodwa kungase kube nokuphikiswa ezilwaneni eziseduze nokuhlatshwa.

 Ezimvini, i-levamisole ingabangela ukujabula kwesikhashana kwezinye izilwane ngemva komthamo. Ezimbuzini, i-levamisole ingabangela ukucindezeleka, i-hyperesthesia kanye namathe.
 Ezingulubeni, i-levamisole ingase ibangele ukuqhiphuka amathe noma amafinyila. Izingulube ezingenwe izikelemu zamaphaphu zingase zikhwehlele noma ziphalaze.

 Imiphumela emibi engase ibonakale ezinjeni ihlanganisa ukuphazamiseka kwe-GI (imvamisa ukuhlanza, isifo sohudo), i-neurotoxicity (ukuhefuzela, ukuthuthumela, ukuyaluza noma ezinye izinguquko zokuziphatha), i-agranulocytosis, i-dyspnea, i-pulmonary edema, ukuqhuma kwesikhumba okubangelwa amasosha omzimba (i-erythroedema, i-erythema multiforme, ubuthi). i-epidermal necrolysis) kanye nokukhathala.

 Imiphumela emibi ebonakala kumakati ihlanganisa i-hypersalivation, injabulo, i-mydriasis nokuhlanza.
 

Okokuphatha ngomlomo.

Umthamo ojwayelekile ngu-5-7.5 mg Levamisole ngekhilogremu ngayinye yesisindo somzimba.

Ukuze uthole imininingwane eyengeziwe ehlobene ne-bolus ngayinye, bheka ithebula elingezansi.

I-Bolus Dosage:

150mg 1 bolus ngesisindo somzimba esingama-25kg.

600mg 1 bolus nge-100kg yesisindo somzimba.

I-1000mg 1 bolus ngesisindo somzimba esingu-150kg.

Izinkomo (inyama ne-offal): izinsuku ezi-5.

Izimvu (inyama ne-offal): izinsuku ezi-5.

Akufanele isetshenziswe ezilwaneni ezikhiqiza ubisi oluzodliwa abantu.

Izinga lokushisa eliphezulu elinconyiwe lesitoreji ngu-30℃.

Isexwayiso:Gcina lapho izingane zingafinyeleleki khona.