Neomycin Sulfate Soluble Powder
Neomycin pūkawa
Ko tenei hua he momo ma ki te paura kowhai marama.
Pharmacodynamics Ko te Neomycin he rongoa paturopi i ahu mai i te raihi hydrogen glycoside. He rite te tuāwhiorangi antibacterial ki te kanamycin. He kaha antibacterial i runga i te nuinga o nga huakita karamu-kino, penei i te Escherichia coli, Proteus, Salmonella me Pasteurella multocida, a he tairongo hoki ki te Staphylococcus aureus. Pseudomonas aeruginosa, huakita karamu-pai (haunga te Staphylococcus aureus), Rickettsia, anaerobes me te harore he ātete ki tenei hua.
Pharmacokinetics Ko te Neomycin he uaua ka uru i muri i te whakahaere waha me te tono a-rohe. I muri i te whakahaere a-waha, ko te 3% anake o te nui o te neomycin ka puta mai i te mimi, a ko te nuinga o te waa ka peia mai i nga feces kaore he huringa. Ko te mumura o te mucosa intestinal me te whewhe ka nui ake te whakauru. Ka tere te horomitanga o te rongoa i muri i te werohanga, a, he rite tonu te tukanga o roto ki te kanamycin.
(1) Whakakotahitia me nga paturopi macrolide, ka taea e ia te rongoa i te mastitis na te huakita karamu pai.
(2) Ka taea e te whakahaere-waha te pa ki te whakauru o te digitalis, te huaora A, te huaora B12 ranei.
(3) He mahi whakakotahi me te penicillin me te cephalosporin ranei.
(4) Ko te hua antibacterial o tenei hua ka whakareihia i roto i te taiao kawakore, a he hototahi ki nga raau taero kawakore (pēnei i te konutai bicarbonate, aminophylline Me etahi atu) ka taea te whakarei ake i te paanga antibacterial, engari ko te paitini ka piki ake ano. Antibacterial ka nui ake te pH 8.4 Engari, ka ngoikore te paanga.
(5) Ka taea e nga Cations penei i te Ca2+, Mg2+, Na+, NH me K+ te aukati i te mahi antibacterial o te hua.
(6) Whakakotahitia me te cephalosporin, te dextran, nga diuretics kaha (penei i te furosemide), erythromycin, me etahi atu, ka taea te Whakanuia te ototoxicity o tenei hua.
(7) Ko nga mea whakangawari i nga uaua o te koiwi (penei i te succinylcholine chloride) me nga raau taero me tenei paanga ka taea te whakapakari i te awenga poraka Neuromuscular.
Aminoglycoside antibiotic. Ka whakamahia te nuinga ki te whakamaroke ki te rongoa i te mate gastrointestinal na te huakita karamu-kino tairongo.
Ka tatauhia e tenei hua. Te inu whakauru: 1.54~2.31g heihei mo ia 1L wai. Ka taea te whakamahi tonu mo nga ra 3 ~ 5.
Ko te Neomycin te tino paitini i roto i nga aminoglycosides, engari he iti noa nga tauhohenga paitini ka puta ina tukuna ma te waha, ma te rohe ranei.
Ko nga heihei e whakaohua ana hei kai ma te tangata, kaua e whakamahia i roto i te waa whakapanga.
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