Neomycin Sulfate Powder enyibilikayo

Neomycin sulfate

Le mveliso luhlobo lomgubo olumhlophe ukuya kolutyheli okhanyayo.

I-Pharmacodynamics I-Neomycin lichiza lokulwa ne-antibacterial eliphuma kwi-hydrogen glycoside rice. I-antibacterial spectrum yayo ifana ne-kanamycin. Inefuthe elinamandla lokulwa ne-antibacterial kwiibhaktheriya ezininzi ze-gram-negative, ezifana ne-Escherichia coli, i-Proteus, i-Salmonella kunye ne-Pasteurella multocida, kwaye inovelwano kwi-Staphylococcus aureus. I-Pseudomonas aeruginosa, ibhaktheriya e-gram-positive (ngaphandle kwe-Staphylococcus aureus), i-Rickettsia, i-anaerobes kunye nefungi zixhathisa le mveliso.
I-Pharmacokinetics Neomycin ayifane ifunnwe emva kokulawulwa komlomo kunye nesicelo sendawo. Emva kokulawulwa komlomo, kuphela i-3% yexabiso lilonke le-neomycin likhutshwe kumchamo, kwaye ininzi yalo ikhutshwe kwindle ngaphandle kokutshintsha. Intestinal mucosa ukudumba okanye izilonda kunokonyusa ukufunxa. Ichiza lifunxwa ngokukhawuleza emva kokutofa, kwaye inkqubo yalo yangaphakathi ifana ne-kanamycin.

(1) Idityaniswe ne-macrolide antibiotics, inokunyanga isifo sokukrala kwebele esibangelwa yintsholongwane yegram-positive.
(2) Ukulawulwa komlomo kunokuchaphazela ukufunxwa kwe-digitalis, i-vitamin A okanye i-vitamin B12.
(3) Inefuthe le-synergistic kunye ne-penicillin okanye i-cephalosporin.
(4) Impembelelo ye-antibacterial yale mveliso iphuculwe kwindawo ye-alkaline, kwaye iyahambelana neziyobisi ze-alkaline (ezifana ne-sodium bicarbonate, i-aminophylline kunye nokunye) kunokunyusa umphumo we-antibacterial, kodwa i-toxicity nayo iphuculwe ngokuhambelanayo. I-Antibacterial xa i-pH idlula i-8.4 Ngokuchasene noko, umphumo ubuthathaka.
(5) I-Cations efana ne-Ca2 +, i-Mg2 +, i-Na +, i-NH kunye ne-K + inokuthintela umsebenzi we-antibacterial wemveliso.
(6) Ngokudibanisa ne-cephalosporin, i-dextran, i-diuretics enamandla (njenge-furosemide), i-erythromycin, njl., Inokuphucula i-ototoxicity yale mveliso.
(7) I-skeletal muscle relaxants (efana ne-succinylcholine chloride) okanye iziyobisi ezinolu mphumo zinokuqinisa i-Neuromuscular block effect.

Aminoglycoside antibiotics. Ikakhulu isetyenziselwa ukomisa unyango losulelo lwesisu olubangelwa ziintsholongwane ezibuthathaka zegram-negative.

Kubalwa yile mveliso. Ukusela okuxutyiweyo: 1.54 ~ 2.31g yenkukhu nge-1L yamanzi. Ingasetyenziswa ngokuqhubekayo kwi-3 ~ 5 iintsuku.

I-Neomycin yeyona tyhefu kwi-aminoglycosides, kodwa zimbalwa iintshukumo eziyityhefu ezenzekayo xa isetyenziswa ngomlomo okanye ekuhlaleni.

Iinkukhu ezibeka amaqanda ukuze zityiwe ngabantu aziyi kusetyenziswa ngexesha lokubeka.

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