Neomycin Sulfate Soluble Powder

Neomycin sulphate

Izi ndi mtundu wa ufa woyera mpaka kuwala wachikasu.

Pharmacodynamics Neomycin ndi antibacterial mankhwala opangidwa kuchokera ku hydrogen glycoside mpunga. Ma antibacterial spectrum ake ndi ofanana ndi a kanamycin. Imakhala ndi antibacterial wamphamvu pa mabakiteriya ambiri omwe alibe gramu, monga Escherichia coli, Proteus, Salmonella ndi Pasteurella multocida, komanso amakhudzidwa ndi Staphylococcus aureus. Pseudomonas aeruginosa, mabakiteriya omwe ali ndi gramu (kupatula Staphylococcus aureus), Rickettsia, anaerobes ndi bowa sagonjetsedwa ndi mankhwalawa.
Pharmacokinetics Neomycin kawirikawiri odzipereka pambuyo m`kamwa makonzedwe ndi m`deralo ntchito. Pambuyo pakamwa, 3% yokha ya neomycin yonse imatulutsidwa mumkodzo, ndipo zambiri zimachotsedwa ku ndowe popanda kusintha. Kutupa kapena zilonda zam'mimba zimatha kuwonjezera kuyamwa. Mankhwalawa amatengedwa mwamsanga pambuyo jekeseni, ndipo mkati mwake ndi ofanana ndi a kanamycin.

(1) Kuphatikiza ndi ma macrolide antibiotics, imatha kuchiza mastitis omwe amayamba chifukwa cha mabakiteriya a gram-positive.
(2) Kuwongolera pakamwa kungakhudze kuyamwa kwa digitalis, vitamini A kapena vitamini B12.
(3) Ili ndi synergistic kwenikweni ndi penicillin kapena cephalosporin.
(4) Mphamvu ya antibacterial ya mankhwalawa imakulitsidwa m'malo amchere, ndipo imagwirizana ndi mankhwala amchere (monga sodium bicarbonate, aminophylline Ndi zina zotero) imatha kupititsa patsogolo mphamvu ya antibacterial, koma kawopsedwe kawo kawongoleredwanso. Antibacterial pamene pH iposa 8.4 M'malo mwake, zotsatira zake zimakhala zofooka.
(5) Ma Cations monga Ca2 +, Mg2 +, Na +, NH ndi K + amatha kulepheretsa ntchito ya antibacterial ya mankhwala.
(6) Kuphatikizidwa ndi cephalosporin, dextran, okodzetsa amphamvu (monga furosemide), erythromycin, ndi zina zotero, kumatha Kupititsa patsogolo kuopsa kwa mankhwalawa.
(7) Kupumula kwa minofu ya m'mafupa (monga succinylcholine chloride) kapena mankhwala omwe ali ndi zotsatirazi akhoza kulimbikitsa Neuromuscular block effect.

Mankhwala a Aminoglycoside. Amagwiritsidwa ntchito kwambiri poumitsa matenda a m'mimba omwe amayamba chifukwa cha mabakiteriya a gram-negative.

Kuwerengeredwa ndi mankhwalawa. Kumwa kosakanikirana: 1.54 ~ 2.31g nkhuku pa 1L yamadzi. Itha kugwiritsidwa ntchito mosalekeza kwa masiku 3-5.

Neomycin ndi poizoni kwambiri mu aminoglycosides, koma ndi poizoni ochepa omwe amapezeka akamaperekedwa pakamwa kapena kwanuko.

Nkhuku zoikira mazira kuti anthu azidya siziyenera kugwiritsidwa ntchito panthawi yoikira.

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