Neomycin Sulfate Soluble Hmoov

Neomycin sulfate

Cov khoom no yog ib hom dawb rau lub teeb daj hmoov.

Pharmacodynamics Neomycin yog cov tshuaj tua kab mob uas tau txais los ntawm hydrogen glycoside mov. Nws antibacterial spectrum zoo ib yam li cov kanamycin. Nws muaj cov tshuaj tua kab mob muaj zog rau feem ntau cov kab mob gram-tsis zoo, xws li Escherichia coli, Proteus, Salmonella thiab Pasteurella multocida, thiab tseem nkag siab rau Staphylococcus aureus. Pseudomonas aeruginosa, kab mob gram-zoo (tshwj tsis yog Staphylococcus aureus), Rickettsia, anaerobes thiab fungi tiv taus cov khoom no.
Pharmacokinetics Neomycin tsis tshua nqus tau tom qab kev tswj hwm qhov ncauj thiab kev siv hauv zos. Tom qab kev tswj hwm qhov ncauj, tsuas yog 3% ntawm tag nrho cov nyiaj neomycin raug tso tawm los ntawm cov zis, thiab feem ntau ntawm nws tau tawm los ntawm cov quav yam tsis hloov pauv. Txoj hnyuv mucosa o los yog rwj tuaj yeem ua rau kom nqus tau. Cov tshuaj tau nqus sai sai tom qab txhaj tshuaj, thiab nws cov txheej txheem sab hauv zoo ib yam li kanamycin.

(1) Ua ke nrog cov tshuaj tua kab mob macrolide, nws tuaj yeem kho mastitis los ntawm cov kab mob gram-zoo.
(2) Kev tswj qhov ncauj tuaj yeem cuam tshuam rau kev nqus ntawm digitalis, vitamin A lossis vitamin B12.
(3) Nws muaj cov nyhuv synergistic nrog penicillin lossis cephalosporin.
(4) Cov nyhuv antibacterial ntawm cov khoom no yog txhim kho nyob rau hauv alkaline ib puag ncig, thiab nws yog sib xws nrog alkaline tshuaj (xws li sodium bicarbonate, aminophylline thiab hais txog) tuaj yeem txhim kho cov nyhuv antibacterial, tab sis cov tshuaj toxicity kuj tseem txhim kho. Antibacterial thaum pH siab tshaj 8.4 Ntawm qhov tsis sib xws, cov nyhuv tsis muaj zog.
(5) Cations xws li Ca2+, Mg2+, Na+, NH thiab K+ tuaj yeem cuam tshuam cov kab mob ntawm cov khoom.
(6) Ua ke nrog cephalosporin, dextran, muaj zog diuretics (xws li furosemide), erythromycin, thiab lwm yam, nws tuaj yeem txhim kho ototoxicity ntawm cov khoom no.
(7) Cov leeg pob txha (xws li succinylcholine chloride) lossis cov tshuaj uas muaj cov nyhuv no tuaj yeem ntxiv dag zog rau Neuromuscular block effect.

Aminoglycoside tshuaj tua kab mob. Nws yog tsuas yog siv los qhuav kho mob plab hnyuv kab mob los ntawm cov kab mob gram-negative rhiab heev.

Muab xam los ntawm cov khoom no. Mixed haus: 1.54 ~ 2.31g nqaij qaib ib 1L dej. Nws tuaj yeem siv tsis tu ncua rau 3 ~ 5 hnub.

Neomycin yog cov tshuaj lom ntau tshaj plaws hauv aminoglycosides, tab sis ob peb cov tshuaj lom neeg tshwm sim thaum nws raug tswj hwm qhov ncauj lossis hauv zos.

Cov qaib uas nteg qe rau tib neeg noj yuav tsum tsis txhob siv thaum lub sij hawm tso.

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