ʻO Neomycin Sulfate Soluble Powder

Neomycin sulfate

ʻO kēia huahana he ʻano keʻokeʻo i ka pauka melemele māmā.

ʻO Pharmacodynamics Neomycin kahi lāʻau antibacterial i loaʻa mai ka laiki hydrogen glycoside. Ua like kona ano antibacterial me kanamycin. Loaʻa iā ia ka hopena antibacterial ikaika i ka hapa nui o nā huakini gram-negative, e like me Escherichia coli, Proteus, Salmonella a me Pasteurella multocida, a ua maʻalahi hoʻi i Staphylococcus aureus. ʻO Pseudomonas aeruginosa, gram-positive bacteria (koe wale nō Staphylococcus aureus), Rickettsia, anaerobes a me nā haʻiki ke kū i kēia huahana.
Pharmacokinetics Neomycin ʻaʻole i komo ma hope o ka lawelawe waha a me ka noi kūloko. Ma hope o ka lawelawe waha, ʻo 3% wale nō o ka nui o ka neomycin i hoʻokuʻu ʻia mai ka mimi, a ʻo ka hapa nui o ia mea i hoʻokuʻu ʻia mai nā feces me ka loli ʻole. Hiki ke hoʻonui i ka absorption o ka mucosa intestinal a i ʻole nā ​​maʻi ʻeha. Hoʻopili koke ʻia ka lāʻau lapaʻau ma hope o ka hoʻopiʻi ʻana, a ua like kona kaʻina kūloko me ka kanamycin.

(1) Hoʻohui pū ʻia me nā lāʻau lapaʻau macrolide, hiki iā ia ke mālama i ka mastitis i hoʻokumu ʻia e ka hua bacteria gram-positive.
(2) Hiki i ka hoʻoponopono waha ke hoʻopili i ka lawe ʻana o ka digitalis, ka huaora A a i ʻole ka huaora B12.
(3) Loaʻa ka hopena synergistic me ka penicillin a i ʻole cephalosporin.
(4) Hoʻonui ʻia ka hopena antibacterial o kēia huahana i loko o ke kaiapuni alkaline, a ua kūpono ia me nā lāʻau alkaline (e like me ka sodium bicarbonate, aminophylline A pēlā aku) hiki ke hoʻonui i ka hopena antibacterial, akā ua hoʻonui ʻia ka toxicity. Antibacterial inā ʻoi aku ka pH ma mua o 8.4 Ma kahi ʻē aʻe, nāwaliwali ka hopena.
(5) Hiki i nā Cations e like me Ca2+, Mg2+, Na+, NH a me K+ ke kāohi i ka hana antibacterial o ka huahana.
(6) Hoʻohui pū me cephalosporin, dextran, diuretics ikaika (e like me furosemide), erythromycin, etc., hiki iā ia ke hoʻonui i ka ototoxicity o kēia huahana.
(7) Hiki i nā mea hoʻomaha o ka ʻiʻo iwi (e like me ka succinylcholine chloride) a i ʻole nā ​​lāʻau me kēia hopena ke hoʻoikaika i ka hopena Neuromuscular block.

ʻO nā lāʻau lapaʻau aminoglycoside. Hoʻohana nui ʻia e hoʻomaloʻo i ka mālama ʻana i ka maʻi gastrointestinal i hoʻokumu ʻia e ka maʻi bacteria gram-negative koʻikoʻi.

Ua helu ʻia e kēia huahana. Ka inu ʻana: 1.54~2.31g moa no ka 1L o ka wai. Hiki ke hoʻohana mau ʻia no 3-5 mau lā.

ʻO ka Neomycin ka mea ʻawaʻawa loa i loko o nā aminoglycosides, akā liʻiliʻi nā hopena ʻawaʻawa i loaʻa ke lawelawe ʻia ma ka waha a i ʻole ma ka ʻāina.

ʻAʻole hoʻohana ʻia nā moa e hoʻomoe ana i nā hua no ka ʻai ʻana o ke kanaka i ka wā hoʻomoe.

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