ʻO Erythromycin Thiocyanate Soluble Powder

Erythromycin

He keʻokeʻo a aneane keʻokeʻo kēia huahana.

ʻO Pharmacodynamics Erythromycin kahi lāʻau lapaʻau macrolide. ʻO ka hopena o kēia huahana i ka maʻi bacteria gram-positive ua like ia me ka penicillin, akā ʻoi aku ka laulā o kāna ʻano antibacterial ma mua o ka penicillin. ʻO nā maʻi maʻi gram-maikaʻi maʻamau ka Staphylococcus aureus (me ka penicillin resistant Staphylococcus aureus), pneumococcus, streptococcus, anthrax, erysipelas suis, listeria, clostridium putrescens, clostridium anthracis, etc. Eia kekahi, he hopena maikaʻi nō hoʻi ia ma Campylobacter, Mycoplasma, Chlamydia, Rickettsia a me Leptospira. Ua hoʻonui ʻia ka hana antibacterial o ka erythromycin thiocyanate i ka hopena alkaline. I ka piʻi ʻana o ka pH mai 5.5 a i 8.5, ua hoʻonui mālie ka hana antibacterial. ʻO ka Pharmacokinetics Erythromycin base a me ka stearate he maʻalahi ke hoʻohaʻahaʻa ʻia e ka ʻakika ʻōpū ke lawe ʻia ma ka waha. ʻO ke ʻano a me ke ʻano o ka paʻakai Erythromycin, ka acidity o ka ʻōpū o ka ʻōpū a me ka meaʻai i loko o ka ʻōpū e pili ana i kona bioavailability. Hiki ke hoʻopili maikaʻi ʻia nā mea hoʻomākaukau i uhi ʻia enteric. Ma hope o ka absorption, laha nui ia i loko o nā ʻiʻo like ʻole a me nā wai o ke kino, akā ʻaʻole hiki ke komo i loko o ka wai cerebrospinal. ʻO ka nui o ka hoʻopaʻa ʻana i ka protein plasma. 73%~81%。 ʻO kahi hapa liʻiliʻi o ka erythromycin ua hoʻololi ʻia e like me ka N-methyl erythromycin inactive i loko o ke akepaʻa, kahi i hoʻokuʻu ʻia ma ka prototype bile. ʻO 2% ~ 5% wale nō o ka nui i hoʻokuʻu ʻia i ka urine prototype.

(1) ʻAʻole kūpono kēia huahana no ka hoʻohana ʻana i ka manawa like me nā macrolides a me nā lincomamine ʻē aʻe ma muli o ka pahuhopu like.

(2) Ke hui pū me B-lactam, loaʻa iā ia ka hopena antagonistic.

(3) Hiki iā ia ke kāohi i ka ʻōnaehana cytochrome oxidase, a hiki ke pale i kāna metabolism ke hoʻohana ʻia me kekahi mau lāʻau.

ʻO nā lāʻau lapaʻau Macrolide. Hoʻohana ʻia ia no ka mālama ʻana i nā maʻi infectious i hoʻokumu ʻia e ka bacteria gram-positive a me ka mycoplasma i loko o nā moa. E like me ka ma'i staphylococcal, ma'i streptococcal, ma'i hanu mau a me ka rhinitis infectious i loko o ka moa.

Ua helu ʻia e kēia huahana. Mea inu i hui ʻia: 2.5g moa no 1L wai. Hiki ke hoʻohana mau ʻia no 3-5 mau lā.

 Ma hope o ka hoʻohana ʻana i ka waha, loaʻa pinepine nā holoholona i nā maʻi o ka maʻi gastrointestinal, e like me ka diarrhea.

(1) ʻAʻole e hoʻohana ʻia nā moa e hoʻomoe ana i nā hua no ka ʻai kanaka i ka wā hoʻomoe.
(2) ʻAʻole kūpono kēia huahana me nā mea waikawa.

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