Erythromycin Thiocyanate Soluble Hmoov

Erythromycin

Cov khoom no yog dawb los yog yuav luag dawb hmoov.

Pharmacodynamics Erythromycin yog tshuaj tua kab mob macrolide. Cov nyhuv ntawm cov khoom no ntawm cov kab mob gram-zoo zoo ib yam li penicillin, tab sis nws cov tshuaj tua kab mob yog dav dua penicillin. Cov kab mob gram-zoo kab mob muaj xws li Staphylococcus aureus (xws li penicillin resistant Staphylococcus aureus), pneumococcus, streptococcus, anthrax, erysipelas suis, listeria, clostridium putrescens, clostridium anthracis, thiab lwm yam. Cov kab mob rhiab heev, muaj xws li cov kab mob sensitive, B ella, Pasteurella, thiab lwm yam, nws kuj muaj txiaj ntsig zoo rau Campylobacter, Mycoplasma, Chlamydia, Rickettsia thiab Leptospira. Cov tshuaj tua kab mob ntawm erythromycin thiocyanate hauv cov tshuaj alkaline tau txhim kho. Thaum pH nce ntawm 5.5 mus rau 8.5, cov tshuaj tua kab mob maj mam nce. Pharmacokinetics Erythromycin puag thiab stearate yog ib qho yooj yim rau degraded los ntawm gastric acid thaum noj qhov ncauj. Hom thiab ntau npaum li cas ntawm Erythromycin ntsev, acidity ntawm txoj hnyuv thiab cov zaub mov hauv plab tag nrho cuam tshuam rau nws cov bioavailability. Tsuas yog enteric coated npaj tuaj yeem nqus tau zoo dua. Tom qab nqus tau, nws tau nthuav dav hauv ntau cov ntaub so ntswg thiab cov kua dej hauv lub cev, tab sis tsis tshua nkag mus rau hauv cov kua cerebrospinal. Lub plasma protein khi tus nqi yog. 73% ~ 81%. Ib feem me me ntawm erythromycin yog metabolized raws li tsis muaj zog N-methyl erythromycin nyob rau hauv daim siab, uas yog tsuas yog tso tawm nyob rau hauv cov qauv bile. Tsuas yog 2% ~ 5% ntawm cov koob tshuaj tau tawm hauv cov zis tso zis.

(1) Cov khoom no tsis haum rau kev siv tib lub sijhawm li lwm cov macrolides thiab lincomamines vim yog tib lub hom phiaj.

(2) Thaum ua ke nrog B-lactam, nws muaj antagonistic nyhuv.

(3) Nws tuaj yeem cuam tshuam cytochrome oxidase system, thiab tuaj yeem cuam tshuam nws cov metabolism thaum siv nrog qee cov tshuaj.

Macrolide tshuaj tua kab mob. Nws yog siv los kho cov kab mob sib kis los ntawm kab mob gram-zoo thiab mycoplasma hauv qaib. Xws li kab mob staphylococcal, kab mob streptococcal, kab mob ua pa ntev thiab kab mob rhinitis hauv qaib.

Muab xam los ntawm cov khoom no. Mixed haus: 2.5g nqaij qaib ib 1L dej. Nws tuaj yeem siv tsis tu ncua rau 3 ~ 5 hnub.

 Tom qab kev tswj hwm qhov ncauj, tsiaj feem ntau muaj cov kab mob raws plab, xws li raws plab.

(1) Cov qaib tso qe rau tib neeg noj yuav tsum tsis txhob siv thaum lub sij hawm tso.
(2) Cov khoom no yuav tsum tsis txhob sib haum nrog cov tshuaj acidic.

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