I-Erythromycin Thiocyanate Powder Encibilikayo

I-Erythromycin

Lo mkhiqizo umhlophe noma ucishe ube yimpushana emhlophe.

I-Pharmacodynamics Erythromycin iyi-antibiotic ye-macrolide. Umphumela walo mkhiqizo kubhaktheriya e-gram-positive ufana ne-penicillin, kodwa i-spectrum yayo ye-antibacterial ibanzi kune-penicillin. Amagciwane azwela igram-positive ahlanganisa i-Staphylococcus aureus (kuhlanganise ne-Staphylococcus aureus ekwazi ukumelana ne-penicillin), i-pneumococcus, i-streptococcus, i-anthrax, i-erysipelas suis, i-listeria, i-clostridium putrescens, i-clostridium anthracis, njll. I-Pasteurella, njll Ngaphezu kwalokho, ibuye ibe nemiphumela emihle kuCampylobacter, Mycoplasma, Chlamydia, Rickettsia kanye neLeptospira. Umsebenzi we-antibacterial we-erythromycin thiocyanate kusisombululo se-alkali wathuthukiswa. Lapho i-pH ikhuphuka isuka ku-5.5 iye ku-8.5, umsebenzi we-antibacterial wanda kancane kancane. I-Pharmacokinetics I-Erythromycin base kanye ne-stearate kulula ukucekelwa phansi yi-asidi yesisu uma ithathwa ngomlomo. Uhlobo nomthamo we-Erythromycin usawoti, i-acidity ye-gastrointestinal tract kanye nokudla esiswini konke kuthinta i-bioavailability yayo. Amalungiselelo ane-enteric kuphela angamuncwa kangcono. Ngemva kokumuncwa, isatshalaliswa kabanzi ezicutshini ezihlukahlukene kanye noketshezi lomzimba, kodwa kuyaqabukela ingene ku-cerebrospinal fluid. Izinga lokubopha amaprotheni e-plasma ngu. 73%~81%。 Ingxenye encane ye-erythromycin igaywe njenge-N-methyl erythromycin engasebenzi esibindini, ekhishwa ikakhulukazi ku-bile ye-prototype. I-2% ~ 5% kuphela yomthamo ikhishwa kumchamo we-prototype.

(1) Lo mkhiqizo awufanele ukusetshenziswa ngesikhathi esifanayo namanye ama-macrolide nama-lincomamine ngenxa yethagethi efanayo.

(2) Uma ihlanganiswa ne-B-lactam, inomphumela ophikisayo.

(3) Ingavimbela uhlelo lwe-cytochrome oxidase, futhi ingase ivimbele umzimba wayo uma isetshenziswa nezidakamizwa ezithile.

Ama-antibiotic e-Macrolide. Isetshenziselwa ukwelapha izifo ezithathelwanayo ezibangelwa amagciwane e-gram-positive kanye ne-mycoplasma ezinkukhu. Njengesifo se-staphylococcal, isifo se-streptococcal, isifo sokuphefumula esingapheli kanye ne-rhinitis ethathelwanayo ezinkukhu.

Kubalwe yilo mkhiqizo. Isiphuzo esihlanganisiwe: 2.5g yenkukhu nge-1L yamanzi. Ingasetshenziswa ngokuqhubekayo izinsuku ezingu-3-5.

 Ngemuva kokuphathwa ngomlomo, izilwane zivame ukuba nokuphazamiseka kwesisu okuncike kumthamo, njengohudo.

(1) Izinkukhu ezizalela amaqanda ukuze zidliwe abantu akufanele zisetshenziswe ngesikhathi sokuzalela.
(2) Lo mkhiqizo akufanele uhambisane nezinto ezine-asidi.

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