Ọgwụ nke Enrofloxacin

Enrofloxacin

Ngwaahịa a enweghị ụcha ka ọ dị ọcha na-acha odo odo.

Pharmacodynamic Enrofloxacin bụ ọgwụ nje na-egbu egbu nke a na-eji eme ihe maka anụmanụ fluoroquinolone. Maka e. coli, salmonella, klebsiella, brucella, pasteurella, pleuropneumonia actinobacillus, erysipelas, bacillus proteus, clayey Mr Charest's bacteria, suppurative corynebacterium, meriri ọbara pott's bacteria, staphylococcus aureus, mycoplasma, chlamygin, na ihe niile na-arụ ọrụ nke ọma nke peruudosa. na streptococcus adịghị ike, mmetụta adịghị ike na nje bacteria anaerobic. Ọ nwere mmetụta doro anya post-antibacterial na nje bacteria nwere mmetụta. Usoro ọrụ antibacterial nke ngwaahịa a bụ igbochi nje nje DNA ntụgharị, na-egbochi mmegharị, ndegharị na nrụzi nke nchikota DNA nke nje bacteria, nje enweghị ike itolite ma mụta nwa nke ọma wee nwụọ.

Pharmacokinetics A na-etinye ọgwụ ahụ ngwa ngwa yana kpamkpam site na ịgba ọgwụ intramuscular. The bioavailability bụ 91.9% na ezi na 82% na ehi. A na-ekesa ya na anụmanụ ma nwee ike ịbanye n'anụ ahụ na mmiri mmiri nke ọma. Ewezuga mmiri mmiri cerebrospinal, ntinye ọgwụ n'ihe fọrọ nke nta ka ọ bụrụ anụ ahụ niile dị elu karịa na plasma. Isi metabolism nke imeju bụ iwepụ ethyl nke mgbanaka 7-piperazine iji mepụta ciprofloxacin, na-esote oxidation na glucuronic acid. tumadi site na akụrụ (renal tubular secretion na glomerular filtration) mwepu, 15% ~ 50% n'ụdị mbụ site na mmamịrị. Mwepụ ọkara ndụ nke ịgba ọgwụ intramuscular bụ awa 5.9 na ehi mmiri ara ehi, awa 1.5 ~ 4.5 na atụrụ, na awa 4.6 na ezì.

(1) Ngwaahịa a nwere mmetụta synergistic mgbe ejikọtara ya na aminoglycosides ma ọ bụ penicillin sara mbara.

(2) Ca2+, Mg2+, Fe3+, Al3+ na ndị ọzọ dị arọ metal ion nwere ike chelate na ngwaahịa a, na-emetụta absorption.

(3) Mgbe ejikọtara ya na theophylline na caffeine, ọnụ ọgụgụ njikọ protein plasma na-ebelata, mkpokọta theophylline na caffeine dị n'ọbara na-abawanye nke ukwuu.

Ọbụlagodi ihe mgbaàmà na-egbu egbu theophylline.

(4) Ngwaahịa a nwere mmetụta nke inhibiting imeju ọgwụ enzymes, nke nwere ike ibelata mkpochapụ ọnụego nke ọgwụ tumadi metabolized na imeju, na-abawanye ọbara ịta nke ọgwụ.

[Ọrụ na ojiji] Quinolones ọgwụ nje antibacterial. A na-eji ya maka ọrịa nje na ọrịa mycoplasma nke anụ ụlọ na anụ ọkụkọ.

Quinolones ọgwụ nje antibacterial. A na-eji ya maka ọrịa nje na ọrịa mycoplasma nke anụ ụlọ na anụ ọkụkọ.

Intramuscular ogwu ogbugba: otu dose, 0.025ml kwa 1kg arọ ahu maka ehi, atụrụ na ezi; Nkịta, nwamba, oke bekee 0.025-0.05 ml. Jiri ya otu ugboro ma ọ bụ ugboro abụọ n'ụbọchị maka ụbọchị abụọ ruo atọ.

(1) Mbelata nke cartilage na-eme na ụmụ anụmanụ na-eto eto, na-emetụta mmepe ọkpụkpụ ma na-akpata claudication na mgbu.

(2) Mmeghachi omume nke usoro nri nri gụnyere vomiting, enweghị agụụ, afọ ọsịsa, wdg.

(3) Mmeghachi omume akpụkpọ ahụ gụnyere erythema, itching, urticaria na mmeghachi omume mmetụta uche.

(4) Mmeghachi omume nfụkasị ahụ, ataxia na ọdịdọ na-ahụ mgbe ụfọdụ na nkịta na nwamba.

(1) Ọ nwere mmetụta na-akpali akpali na sistemụ etiti ma nwee ike ịkpata ọdịdọ epileptic. Ekwesịrị iji nlezianya mee ya na nkịta nwere ọrịa akwụkwụ.

(2) Ndị na-eri anụ na ụmụ anụmanụ na-arụ ọrụ gbasara akụrụ na-adịghị mma na-eji nlezianya eme ihe, nwere ike ime ka mmamịrị kristal mgbe ụfọdụ.

(3) Ngwaahịa a adịghị mma maka nkịta tupu izu asatọ.

(4) Ụdị ọgwụ na-eguzogide ọgwụ nke ngwaahịa a na-abawanye, n'ihi ya, e kwesịghị iji ya mee ihe na subtherapeutic dose ruo ogologo oge.