Gutera Enrofloxacin

Enrofloxacin

Iki gicuruzwa ntigifite ibara ryumuhondo usukuye.

Pharmacodynamic Enrofloxacin ni imiti yagutse ya bagiteri yica udukoko ikoreshwa cyane cyane ku nyamaswa za fluoroquinolone. Kuri e. coli, salmonella, klebsiella, brucella, pasteurella, pleuropneumonia actinobacillus, erysipelas, proteus bacillus, bacteri za clayey Mr Charest, bacteri za suppurative corynebacterium, zatsinze bagiteri zamaraso, staphylococcus aureus, mycoplasma, chlamy na streptococcus ifite intege nke, ingaruka nke kuri bagiteri ya anaerobic. Ifite ingaruka nyuma ya antibacterial kuri bagiteri zoroshye. Uburyo bwa antibacterial action yiki gicuruzwa nuguhagarika ADN ya bagiteri, kubangamira kwigana, kwandukura no gusana ADN ya bagiteri, bagiteri ntishobora gukura no kubyara bisanzwe kandi igapfa.

Pharmacokinetics Umuti winjijwe vuba kandi rwose no gutera inshinge. Bioavailability yari 91.9% mu ngurube na 82% mu nka. Ikwirakwizwa cyane mu nyamaswa kandi irashobora kwinjira mu ngingo no mu mazi neza. Usibye amazi ya cerebrospinal fluid, ubunini bwibiyobyabwenge mubice hafi ya byose biruta ibyo muri plasma. Metabolism nyamukuru ya hepatike ni ugukuraho Ethyl yimpeta 7-piperazine kugirango itange ciprofloxacin, ikurikirwa na okiside hamwe na aside glucuronic ihuza. Ahanini unyuze mu mpyiko (impyiko zo mu bwoko bwa tubular secretion na glomerular filtration) zisohoka, 15% ~ 50% muburyo bwumwimerere kuva inkari. Kurandura igice cyubuzima bwo gutera inshinge ni amasaha 5.9 mu nka zinka, amasaha 1.5 ~ 4.5 mu ntama, namasaha 4,6 mu ngurube.

(1) Iki gicuruzwa gifite ingaruka zo guhuza iyo gihujwe na aminoglycoside cyangwa penisiline yagutse.

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Ndetse ugaragaze ibimenyetso byuburozi bwa theophylline.

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[Uruhare no gukoresha] Imiti igabanya ubukana bwa Quinolones. Ikoreshwa mu ndwara za bagiteri no kwandura mycoplasma y’amatungo n’inkoko.

Quinolones imiti igabanya ubukana. Ikoreshwa mu ndwara ziterwa na bagiteri n'indwara ya mycoplasma y’amatungo n’inkoko.

Gutera inshinge: ikinini kimwe, 0,025ml kuri 1 kg ibiro byumubiri kubwinka, intama ningurube; Imbwa, injangwe, inkwavu 0.025-0.05 ml. Koresha rimwe cyangwa kabiri kumunsi iminsi ibiri cyangwa itatu.

(1) Kwangirika kwa karitsiye bibaho mu nyamaswa zikiri nto, bigira ingaruka kumikurire yamagufa kandi bigatera claudication nububabare.

(2) Imyitwarire ya sisitemu yumubiri harimo kuruka, kubura ubushake bwo kurya, impiswi, nibindi.

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(4) Imyitwarire ya allergie, ataxia no gufatwa rimwe na rimwe bigaragara mu mbwa ninjangwe.

(1) Ifite ingaruka zishimishije kuri sisitemu yo hagati kandi irashobora gutera igicuri. Bikwiye gukoreshwa ubwitonzi mu mbwa zifite igicuri.

(2) Inyamanswa ninyamaswa zifite imikorere mibi yimpyiko ukoresheje ubwitonzi, birashobora rimwe na rimwe gutobora inkari.

(3) Iki gicuruzwa ntikibereye imbwa mbere yibyumweru 8.

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