ʻO Enrofloxacin injection

ʻO Enrofloxacin

ʻAʻole waihoʻoluʻu kēia huahana i ka wai ʻōmaʻomaʻo melemele melemele.

ʻO Pharmacodynamic Enrofloxacin kahi lāʻau bactericidal ākea ākea i hoʻohana kūikawā ʻia no nā holoholona fluoroquinolone. No ka e. coli, salmonella, klebsiella, brucella, pasteurella, pleuropneumonia actinobacillus, erysipelas, bacillus proteus, pālolo ʻo Mr Charest's bacteria, suppurative corynebacterium, lanakila i ka bacteria pott blood, staphylococcus aureus, mycoplasma, chlamydia, etc. a ʻo ka streptococcus he nāwaliwali, nāwaliwali ka hopena i ka maʻi bacteria anaerobic. Loaʻa iā ia ka hopena post-antibacterial ma luna o nā maʻi bacteria koʻikoʻi. ʻO ke ʻano hana antibacterial o kēia huahana ka mea e pale ai i ka huli ʻana o ka DNA bacteria, e hoʻopilikia i ka replication, transcription a me ka hoʻoponopono hou ʻana o ka DNA bacterial recombination, ʻaʻole hiki i ka bacteria ke ulu a hoʻohua maʻamau a make.

Pharmacokinetics Ua hoʻopili koke ʻia ka lāʻau lapaʻau e ka intramuscular injection. ʻO ka bioavailability he 91.9% i nā puaʻa a me 82% i nā bipi. Hoʻolaha nui ʻia i nā holoholona a hiki ke komo maikaʻi i nā ʻiʻo a me nā wai kino. Ma waho aʻe o ka wai cerebrospinal, ʻoi aku ka kiʻekiʻe o ka neʻe ʻana o nā lāʻau i loko o nā kiko āpau ma mua o ka plasma. ʻO ka metabolism hepatic nui ka wehe ʻana i ka ethyl o ke apo 7-piperazine e hana i ka ciprofloxacin, a ukali ʻia e ka oxidation a me ka glucuronic acid binding. ʻO ka mea nui ma o ka puʻupaʻa (renal tubular secretion and glomerular filtration) hoʻokuʻu, 15% ~ 50% i ke ʻano kumu mai ka mimi. ʻO ka hoʻopau ʻana i ka hapalua o ke ola o ka injection intramuscular he 5.9 mau hola i nā bipi waiu, 1.5 ~ 4.5 hola i nā hipa, a me 4.6 mau hola i ka puaʻa.

(1) He hopena synergistic kēia huahana ke hui pū me nā aminoglycosides a i ʻole penicillin ākea ākea.

(2) ʻO Ca2+, Mg2+, Fe3+, Al3+ a me nā ion metala kaumaha ʻē aʻe e hiki ke chelate me kēia huahana, e pili ana i ka absorption.

(3) Ke hui pū ʻia me ka theophylline a me ka caffeine, ua hoʻemi ʻia ka nui o ka hoʻopaʻa ʻana i ka protein plasma, a ua hoʻonui ʻia ke ʻano o ka theophylline a me ka caffeine i ke koko.

ʻIke ʻia nā hōʻailona make theophylline.

(4) ʻO kēia huahana ka hopena o ke kāohi ʻana i nā enzymes lāʻau lapaʻau, hiki ke hōʻemi i ka nui o ka hoʻomaʻemaʻe ʻana o nā lāʻau lapaʻau i hoʻopili nui ʻia i loko o ke ake, a hoʻonui i ke koko o nā lāʻau lapaʻau.

[Role a hoʻohana] Quinolones nā lāʻau antibacterial. Hoʻohana ʻia ia no nā maʻi bacterial a me nā maʻi mycoplasma o nā holoholona a me nā moa.

Nā lāʻau antibacterial Quinolones. Hoʻohana ʻia ia no nā maʻi bacterial a me nā maʻi mycoplasma o nā holoholona a me nā moa.

Intramuscular injection: hoʻokahi pānaʻi, 0.025ml no 1kg paona kino no nā pipi, hipa a me nā puaʻa; ʻO nā ʻīlio, nā pōpoki, nā lapiti 0.025-0.05 ml. E hoʻohana i hoʻokahi a ʻelua paha i ka lā no ʻelua a ʻekolu mau lā.

(1) Loaʻa ka degeneration cartilage i nā holoholona ʻōpio, e pili ana i ka ulu ʻana o ka iwi a hoʻoulu i ka claudication a me ka ʻeha.

(2) ʻO nā hopena o ka ʻōnaehana digestive e pili ana i ka luaʻi ʻana, ka pau ʻana o ka ʻai, ka maʻi maʻi, etc.

(3) Loaʻa i nā hopena o ka ʻili ka erythema, pruritus, urticaria a me ka hopena photosensitive.

(4) ʻIke ʻia nā hopena maʻi, ataxia a me ka hopu ʻana i nā ʻīlio a me nā pōpoki.

(1) Loaʻa iā ia ka hopena excitatory ma ka ʻōnaehana kikowaena a hiki ke hoʻoulu i ka epileptic seizures. Pono e hoʻohana me ka akahele i nā ʻīlio me ka epilepsy.

(2) Hoʻohana ʻia nā mea ʻai a me nā holoholona me ka maikaʻi ʻole o ka hana renal me ka akahele, hiki ke hoʻoheheʻe i ka mimi i kekahi manawa.

(3) ʻAʻole kūpono kēia huahana no nā ʻīlio ma mua o 8 mau pule.

(4) Ke piʻi aʻe nei nā lāʻau kūʻē i ka lāʻau o kēia huahana, no laila ʻaʻole pono e hoʻohana ʻia i ka subtherapeutic dose no ka manawa lōʻihi.